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Unlock a More Radiant Complexion with the CO2RE Laser

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Do you wish you had the kind of complexion that looked bright, vibrant, and radiant – no matter where your day takes you? Do you have dull skin, signs of aging, and loss of skin laxity?

If so, then you may be a good candidate for the CO2RE laser resurfacing treatment, now available at Twin Ports Dermatology in Duluth, MN!

What is the CO2RE Laser?

The CO2RE Laser is an all-in-one laser system that’s designed to treat all your biggest complexion issues, including:

  • Wrinkles and fine lines
  • Loss of skin laxity
  • Hyperpigmentation
  • Sluggish collagen and elastin production
  • And more


The CO2RE Laser achieves these goals by offering a customized “peel” approach, which ensures that every patient is getting the treatment they need. From light laser resurfacing to deep fractional laser resurfacing, the CO2RE Laser can transform your skin any way you’d like.

At Twin Ports Dermatology, we use the CO2RE Laser for many of our laser resurfacing treatments, with an emphasis on treating hyperpigmentation, acne scarring, aging symptoms, and skin laxity issues.

Am I A Good Candidate For CO2RE Laser Treatments?

You’re a good candidate if you have any of the following skin issues:

  • Fine lines and wrinkles
  • Poor skin laxity
  • Hyperpigmentation
  • Acne and trauma scarring
  • Sun spots
  • Dull skin tone
  • Uneven skin texture
  • And more!

How Long Does a Typical Treatment Take?

Each CO2RE treatment is customized to your needs; however, most patients can expect to spend 30 to 60 minutes in a CO2RE treatment session.

Consultations Are Available Now

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Take the first step. Get your questions answered and find out which treatment option is best for your personal situation by meeting with one of our knowledgeable medical staff at Twin Ports Dermatology for an in-person consultation.

Simply fill out the form on this page, and one of our experienced team members will reach out to you promptly to schedule your consultation.

How Should I Prepare for Treatment?

We recommend stopping all use of retinol or similar products known to increase skin sensitivity 1-2 weeks before your laser resurfacing procedure. Acne breakouts or open wounds could also interfere with your treatment, so if these become an issue, please contact us to reschedule. We understand these situations are sometimes out of our control, so we’ll work with you for the best appointment time possible.

What Results Will I See?

Results can include:

  • Fewer wrinkles and lines
  • Improved skin clarity and texture
  • Reduced scarring
  • Reduced hyperpigmentation
  • And more


Most patients need about 2-5 CO2RE treatment sessions to see their ideal results.

Is There Any Downtime?

There’s no downtime associated with your CO2RE laser treatment, although you may experience some redness and mild discomfort at the treatment site. We do ask that you wear a high SPF sunscreen, as your skin will be sensitive to the sun’s UV rays.

Please refer to the packet given during your consultation for pre-treatment, step-by-step instructions.

Many medications make you sensitive to laser procedures and can result in adverse reactions. Below is a list of common medications. If you are on any of these medications, please reschedule your appointment after being off these for two weeks. If your appointment is within two weeks, please call us to reschedule.

Isotretinoin (Accutane)

Adapalene (Differin)

Tretinoin (Retin-A, Renova) 

Dapsone (Aczone)

Acitretin (Soriatane)

Dacarbazine (DTIC-Dome)

Fluorouracil (Fluoroplex, Efudex, 5 FU, Carac)

Methotrexate (Mexate; and others)

Vinblastine (Veiban)

Gold Salt thiomalate (Solganol)

Amitriptyline (Elavil; and others)

Bupropion (Wellbutrin)

Clomipramine (Anafranil)

Desipramine (Norpramin; Petrofrane)

Doxepin (Adapin; Sinequan)

Fluoxetine (Prozac)

Imipramine (Tofranil; and others)


Mirtazapine (Remuron)

Nortriptyline (Aventyl; Pamelor)

Paroxetine (Paxil)

Protriptyline (Vivactil)

Sertraline (Zoloft)

Tricyclics (class) 

Trimipramine (Surmontil)

Flucytosine (Ancobon)


Voricanozole (Vfend)



Cetirizine (Zyrtec)

Cyproheptadine (Periactin)

Diphenhydramine (Benadryl; and others)

Loratadine (Claritin)


Celecoxib (Celebrex)

ibuprofen (Motrin)

Naproxen (Naprosyn)

Piroxicam (Feldene)

Ketoprofen (Frotek)

Azithromycin (Zithromax)

Ciprofloxacin (Cetraxal, Cipro XR)

Dapsone (Aczone)

Demeclocycline (Declomycin; others)

Doxycycline (Vibramycin, Adoxa, Doryx, Periostat, Monodox, Oracea)

Griseofluvin (Fulvicin-U/F;others)



Lomefloxacin (Maxaquin)

Methacycline (Rondomycin)

Minocycline (Solodyn, Minocyn)

Nalidixic acid (NegGram; others)

Oxytetracycline (Terramycin; others)

Quinolones(class) (ofloxacin, Floxin)





Sulfamethoxazole/trimethoprim (Bactrim, Septra)

Sulfasalazine (Azulfadine)


Sulfisoxazole (Gantrisin)

Tetracyclines (class)

Chlorpromazine (Thorazine; and others)

Fluphenazine (Permitil; Prolixin)

Haloperidol (Haldol)

Perphenazine (Trilafon)

Piperacetazine (Quide)

Prochlorperazine (Compazine; and others)


Promethazine (Phenergan; and others)

Thioridazine (Mellaril)

Trifluoperazine (Stelazine; and others)

Triflupromazine (Vesprin)

Trichlormethiazide (Metahydrin; and others)

Thiazides (Diuril; HydroDIURIL)



Acetohexamide (Dymelor)

Trimeprazine (Termaril

Chlorpropamide (Diabinese; Insulase)

Tolazamide (Tolinase) Tolbutamide (Orinase; and others)

Glimepiride (Amaryl)

Glipizide (Glucotrol)

Glyburide (Glynase)

Tolazimide (Tolinase)

Tolbutamide (Orinase;others)

ACE inhibitors (Vasotec)

Amiodarone (Cordarone)

Diltiazem (Cardizem)

Disopyramide (Norpace)


Lovastatin (Mevacor)

Pravastatin (Pravachol)



Simvastatin (Zocor)

(medication used to reduce blood and tissue levels of harmful heavy metals)

Simvastatin (Zocor, FloLipid)

Atorvastatin (Lipitor)

Lovastatin (Altoprev)

Pravastatin (Pravachol)

Acetazolamide (Diamox)

Amiloride (Midamor)

Bendroflumethiazide (Naturetin; and others)

Benzthiazide (exna and others)

Chlorothiazide (Diuril and others)


Cyclothiazide (Anhydron)

Furosemide (Lasix)

Hydroflumethiazide (Diucardin; and others)

Hydrochlorothiazide (HydroDIURIL; and others)

Methyclothiazide (Aquatensen; Enduron)

Metolazone (Diulo; Zaroxolyn)

Polythiazide (Renese)

Quinethazone (Hydromox)

Triamterene (Dyrenium)

Trichlormethiazide (Metahydrin;others)

Thiazides (class)

Estrogen replacement

Oral contraceptives

Other hormones

Additional plant families

Agrimony (Agrimonia eupatoria)

Angelica root and fruit (Angelica species)

Bergamot peel (Citrus bergamia

Bitter orange peel (Citrus aurantium)

Buttercup plant (Ranunculus species)

Carrot family

Celery (Apium graveolens)

Cow Parsnip (Heracleum lanatum)

Dill (Anthium graveolens)

Fennel (Foeniculum vulgare)

Fig (Ficus carica)

Goosefoot (Chenopodium species)

Iron tablets

Khella fruit (Ammi visnaga)

Lemon peel (Citrus limonia)

Lomatium (Lomatium dissectum)

Lovage root (Levisticum officinale)

Parsley (Petroselinum sativum)

Psoralea seeds (Cullen corylifolia, Psoralea corylifolia)

Queen Anne’s lace (Daucus carota)

Rue leaves (Ruta graveolens)

St Johns Wart (Hypericum perforatum)

Yarrow plant (Achillea millefolium)

Methoxsalen (Oxsoralen)


PABA (p-aminobenzoic acid)

Sunscreens containing benzophenones

  • Please refer to the packet given during your consultation for pre-treatment, step-by-step instructions.
  • Your at-home skin care regimen between treatments is as essential as the treatment to reach optimal results.  
  • If you have questions about your treatment, please call us immediately at 218-302-1000. Note we are not open on weekends; if you have a medical concern on the weekend, please visit urgent care. Call us the following Monday so we can assist you.
  • We do request a 24-hour cancellation policy for appointments, please. Failure to do will result in a $50 fee.
  • Refunds on products are for exchange only within 30 days.  Refunds on procedures will receive credit toward future purchases.


*individual results may vary


Take the First Step - Request A Consultation

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If you would like to schedule an in-person consultation, please fill out the form on this page and one of our knowledgeable medical staff members at Twin Ports Dermatology will reach out to you promptly. You can also call our Duluth, MN office directly to schedule: 218-302-1000.

Twin Ports Dermatology serves the greater Duluth area. We’re the only locally owned private dermatology clinic & medspa in the area.

*Individual results may vary